Azithromycin activities against Orientia tsutsugamushi strains isolated in cases of scrub typhus in Northern Thailand.

نویسندگان

  • G Watt
  • P Kantipong
  • K Jongsakul
  • P Watcharapichat
  • D Phulsuksombati
چکیده

Azithromycin was given to mice and humans infected with strains of Orientia tsutsugamushi from northern Thailand, where drug-resistant scrub typhus occurs. Azithromycin and doxycycline yielded comparable mouse survival rates (73 and 79%, respectively; P > 0.5). Symptoms, signs, and fever in two pregnant women abated rapidly with azithromycin. Prospective human trials are needed.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 43 11  شماره 

صفحات  -

تاریخ انتشار 1999